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HEPATITIS NEWS

77 more hepatitis cases may trace to clinic, officials say
LAS VEGAS -- Seventy-seven more people that were treated at a Las Vegas outpatient clinic have been diagnosed with hepatitis C, health officials said. Authorities can't say for sure how the 77 people were infected, said Brian Labus, senior epidemiologist

77 more hepatitis cases may trace to clinic at center of Las Vegas outbreak, officials say
AM LAS VEGAS-Seventy-seven more people that were treated at a Las Vegas outpatient clinic accused of reusing syringes on thousands of people have been diagnosed with Hepatitis C, health officials said. Authorities cannot say for sure how the 77 people

77 more hepatitis cases may trace to clinic, officials say
Seventy-seven more people that were treated at a Las Vegas outpatient clinic have been diagnosed with hepatitis C, health officials said.Authorities can't say for sure how the 77 people were infected, said Brian Labus, senior epidemiologist with the

UPDATES AND COMMENTARY

Highly Effective Against HCV Genotype 1
When tested on people with Hepatitis C genotype 1, R7128 proved to be an effective addition to combination therapy after just four weeks' time. In addition to its anti-viral effect, polymerase inhibitor R7128 received good marks for safety and minimal...

Investigational Drug Beats Standard Therapy in Hepatitis C Study
A Phase IIa trial investigating triple combination therapy with PEGASYS, COPEGUS and Roche's investigational drug R1626, demonstrated a higher response rate than traditional combination therapy alone. While R1626's effectiveness and high barrier to resistance makes it a top Hepatitis C...

Hepatitis C Complications Helped by Maintenance Interferon
A four-year study confirms that low-dosage maintenance interferon therapy prevents disease progression in those with portal hypertension or cirrhosis from Hepatitis C....

Role of Alcohol in the Progression of Liver Disease Caused By Hepatitis C Virus Infection

table 3. Summary of Breakdown of Variables According to Fibrosis Score on Liver Biopsy

Variable	Fibrosis Score
Variable	0 (n = 15)	1 (n = 119)	2 (n = 35)	3 (n = 11)	4 (cirrhosis) (n = 50)

Age (yr)	33.5	37.4	39.1	39.1	51.6^*
Male sex (%)	(31)	(75)	(77)	(78)	(68)
HCV Duration (yr)	15.6	15.7	16.2	24.0	20.1
HCV RNA titre (×10⁵ copies/mL)	3.6	1.6	1.6	4.1	1.9
HCV genotype 1 (%)	(100)	(54)	(62)	(22)	(52)
Lifetime total alcohol (kg)	101	200	185	243	289
Lifetime average daily alcohol (g)	16	27	26	38	27

NOTE. All values expressed as mean except for "male sex" and "genotype 1," which are expressed as percentages. ^* P = .0001; P = .0002.

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