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table  3.   Features of Variant Syndromes Compared With Definite Autoimmune Hepatitis
AIH + PBC (n = 15) AIH + PSC (n = 14) Autoimmune Cholangitis (n = 11) Definite AIH (n = 87)
Age (yr)   52 ± 4   42 ± 4   44 ± 3   44 ± 2
Men/women 2/13 5/9 2/9 12/75
AST (reference value, 31 U/L)  565 ± 159  232 ± 86   237 ± 122##  519 ± 38 ,##
Bilirubin (reference value, 1.1 mg/dL)   6.4 ± 2   2.2 ± 0.5   2.8 ± 1.3   3.9 ± 0.5
Alkaline phosphatase (reference value, 309 U/L)  433 ± 68  843 ± 161* 1045 ± 2442  360 ± 26*,
 -Globulin (reference value, 0.7-1.7 g/dL)   3.3 ± 0.2   2.5 ± 0.3**  1.74 ± 0.23   3.6 ± 0.1,**
Immunoglobulin G (reference value, 700-1500 mg/dL) 2751 ± 222§§§ 2470 ± 330¶¶ 1596 ± 1954§ 3421 ± 132§,¶¶,§§§
Immunoglobulin M (reference value, 60-300 mg/dL)  527 ± 107  232 ± 22  198 ± 30  278 ± 0.2
SMA 1:40 10 (67) 6/13 (46) 5 (45)§§ 78 (90),§§,
ANA 1:40 10 (67) 6 (43)*** 10 (91) 66 (76)***
DR4+ 9 (60) 2 (14) 3/10 (30) 42 (48)
DR3+ 5 (33) 10 (71) 4/10 (40) 43 (49)
Total score  14.5 ± 0.8  14.2 ± 1  10.4 ± 0.9#  18.5 ± 0.2,¶,#
NOTE. Numbers in parentheses are percentages.
Abbreviation: AIH, autoimmune hepatitis.
Significantly different from each other at levels of *,,,§,,,#P < .0001, **P = .0002, P = .0006, P = .0007, §§P = .001, ,¶¶P = .006, ## ,***,P = .02, P = .03, and §§§P = .04.

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