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PEGASYS(R)/COPEGUS(R) Show Benefit in Hard-to-Treat Latino Population with Hepatitis C
- Largest prospective study in under-treated and under-studied population (The LATINO Study) provides important insights - SAN DIEGO, Calif., May 18 /PRNewswire/ -- Roche today announced results from the LATINO study, the largest prospective study to


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What You Must Know About Alcoholic Hepatitis
This much-needed synopsis of alcoholic hepatitis reminds us that you don't need to be a heavy drinker to suffer from this condition. Looking over the causes, risk factors and complications of alcoholic hepatitis will motivate anyone with liver concerns to...

15 Tips for Managing Interferon-Ribavirin Side Effects
Finding new ways to manage the side effects of Hepatitis C combination therapy adds to a person’s likelihood of conquering the virus....

New Mexico Offers Free Hepatitis C Hotline
Finally being recognized as the widespread, public health problem that it is, the New Mexico Department of Health has taken a giant step forward to help people with Hepatitis C. By launching a new, toll-free phone number, locals concerned about...

Modified Staging: architectural changes, fibrosis and cirrhosis*  
Change Score
No fibrosis 0
Fibrous expansion of some portal areas, with or without short fibrous septa 1
Fibrous expansion of most portal areas, with or without short fibrous septa 2
Fibrous expansion of most portal areas with occasional portal to portal (P-P) bridging 3
Fibrous expansion of portal areas with marked bridging [portal to portal (P-P) as well as portal to central (P-C)] 4
Marked bridging (P-P and/or P-C) with occasional nodules (incomplete cirrhosis) 5
Cirrhosis, probable or definite 6
References
  1. Ishak K, et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995;22:696-699.
  2. Knodell RG, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology1981;1(5):431-5
*Additional features which should be noted but not scored: Intra-acinar fibrosis, perivenular ('chicken wire' fibrosis) and phlebosclerosis of terminal hepatic venules.

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Updated 18 May 2008