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New Mexico Offers Free Hepatitis C Hotline
Finally being recognized as the widespread, public health problem that it is, the New Mexico Department of Health has taken a giant step forward to help people with Hepatitis C. By launching a new, toll-free phone number, locals concerned about...
Modified Staging: architectural changes, fibrosis and cirrhosis*
Change
Score
No fibrosis
0
Fibrous expansion of some
portal areas, with or without short fibrous septa
1
Fibrous expansion of most
portal areas, with or without short fibrous septa
2
Fibrous expansion of most
portal areas with occasional portal to portal (P-P) bridging
3
Fibrous expansion of portal
areas with marked bridging [portal to portal (P-P) as well as portal to
central (P-C)]
4
Marked bridging (P-P and/or
P-C) with occasional nodules (incomplete cirrhosis)
5
Cirrhosis, probable or definite
6
References
Ishak K, et al. Histological grading and staging
of chronic hepatitis.
J Hepatol 1995;22:696-699.
Knodell RG, et al. Formulation and application
of a numerical scoring system for assessing histological activity in
asymptomatic chronic active hepatitis. Hepatology1981;1(5):431-5
*Additional features which
should be noted but not scored: Intra-acinar fibrosis, perivenular ('chicken
wire' fibrosis) and phlebosclerosis of terminal hepatic venules.
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