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J Clin Microbiol 1976 May;3(5):465-468
Persistence of antibody to Hepatitis B surface antigen.
Irwin GR, Allen AM, Segal HE, Willhight M, Cannon H, Top FH Jr
Sera from military personnel found to have antibodies to Hepatitis B surface
antigen (anti-HBS) in an epidemiological study of a Hepatitis B outbreak were
tested for persistence of that antibody 1 year later. Initially, 64% of the
anti-HBS-positive sera reacted in passive hemagglutination tests with erythrocytes
coated with Hepatitis B surface antigen of both ayw and adw subtypes; the remaining
sera reacted only with adw-coated erythrocytes (19%) or ayw-coated erythrocytes
(17%). After 1 year, anti-HBS was detectable by passive hemagglutination tests
in 87% of individuals with initial antibody to both subtypes but in only 41%
and 16% (P less than 0.001) of those initially reacting only to adw- or ayw-coated
erythrocytes, respectively. Seropositivity for anti-HBS correlated best with
history of contact with jaundiced people (20.3%) and duty in Asia.
PMID: 932185, UI: 76213617
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