Hepatitis Central

The latest research & treatment news about Hepatitis C infection, diagnosis, symptoms and treatments.

Molecular Basis for Persistent Hepatitis B Virus Infection In the Liver After Clearance of Serum Hepatitis B Surface Antigen

table  1.   Southern Blot Studies of Hepatic Nucleic Acids Amplified by Either RT-PCR Using Primers Complementary to the HBV Core and Surface Genes or Seminested PCR Using Primers Flanking the HBV DR Region
Patients Months After HBsAg Clearance RT-PCR for HBV RNA
Seminested PCR
HBV Core Gene Primers HBV Surface Gene Primers HBV DR Region Primers
Study group*
  1 3 + + +
  2 3 + +   -
  3 9  - + +
  4* 24   -  -  -
  5 46  -   - +
  6 47   -   -   -
  7dagger 67 + +   -
Controls
  HBsAg-positive 12/13 11/13 3/3
  HBsAg-negative 0/4 0/4 0/4
* All study group patients HBV-DNA-positive in the liver by PCR except for patient 4.8 Patients 1, 2, and 3 represent patients 1, 2, and 3 in Kuhns,8 whereas patients 4, 5, 6, and 7 in this table are patients 7, 4, 5, and 6, respectively, as tabulated in Kuhns.8
dagger HBV-DNA-positive in serum by PCR.8

Return to Article

Site Topics

  • Frequently Asked Questions

    Some of our most commonly asked questions and our answers to them.

  • HCV Symptoms

    You'll find links to a comprehensive symptoms list, as well as various studies and discussions about Hepatitis C symptoms.

  • Lab Tests

    What they are and what they mean. Helps you interpret & understand all the various hepatitis lab tests likely to be encountered.

  • Hepatitis C Genotypes

    Learn about Hepatitis C Genotypes and their variants.

  • Viral Load

    Provides detailed information on how to analyze and interpret viral load numbers as well as a link to a convenient Viral Load Chart.

  • What is...?

    Learn more about various Hepatitis C related topics, including HCV, Ascites, Biopsies, and much more.

  • HCV Medicines

    Numerous links to studies, info sheets, FAQs, and analysis of Ribavirin/Rebetron medicines.

  • Glossary

    Commonly used medical terms and definitions.

  • Hepatitis C Doctors

    A state-by-state and worldwide reference listing physicians who treat HCV, including an email link to submit your physician for inclusion.

  • Biopsy Info

    A comprehensive resource of information relating to the liver biopsy.

  • Cirrhosis

    Many discussions and analyses of cirrhosis, including causes, complications, pathology, symptoms, and much more.

  • Liver Cancer

    Liver Cancer/Hepatocellular Carcinoma studies, info sheets, FAQs, and analysis.

  • Liver Disease Medicines

    An exhaustive list of links to studies, info sheets, FAQs, and analysis of the various drugs used to treat liver disease.

  • Hep-Central Email List

    Sign up to learn about advances and breakthroughs in Hepatitis C research, including information about medical and complementary treatments.

  • HCV Links

    Convenient links to other sites external to Hepatitis-Central.

  • HCV Transmission

    Information about the transmission of Hepatitis C.

  • HCV Natural Remedies

    A number of herbal products useful in the management of liver disease.

  • HCV Books

    Recommended reading for those interested in hepatitis information.

  • Hepatitis C Forum

    A Bulletin Board for discussions on hepatitis, treatments, etc.

  • Hepatitis C Activism

    An easy way to get involved in urging our government to do more for Hepatitis C awareness and treatment research.

Advertisement(s)

Advertisement