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Screening for Hepatocellular Carcinoma

table 1. Clinic-Based Surveillance Studies for HCC in Patients With Chronic Viral Hepatitis and Cirrhosis of Mixed Etiology
Author Country Number Screened Incidence of HCC (%/year) % Cirrhosis % Chronic Hepatitis % HBV % HCV HCCs No. found HCCs No. Resected or Treated for Cure
Takano39 Japan 251 1.1 0 100 51 49 19 9
Shea36 Taiwan 528 1 45 15 75 24 5
Curley37 Italy 416 0.8 15 85 18 81 36 22
Tsukuma36 Japan 917 4.1 26 74 8.7 47 54 NA
Tanaka35 Japan 660 2.2 27 73 22 12
Chiba34 Japan 412 0.8 44 56 0 100 63 NA
Solmi40 Italy 360 1.4 70 30 8 72 24 NA
Cottone23 Italy 147 5.6 100 0 14 71 30 2
Zoli24 Italy 164 100 0 34 3
Oka25 Japan 260 4.3 100 0 14 81 62 NA
Benvegnu16 Italy 290 3 100 0 21 64 32 NA
Borzio26 Italy 307 1.4 100 0 17 34 45 NA
Pateron27 France 322 5.8 100 0 14 1
Kato14 Japan 401 5.1 100 0 64 127 NA
Colombo28 Italy 447 2 100 0 11 45 59 12
Zaman29 England 613 1 100 0 7.6 42 NA
Ikeda15 Japan 796 3.8 100 0 33 221 NA
Abbreviations: HCV, hepatitis C virus; NA, not available.

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