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Hepatitis E confirmed in Gulu
Gulu Hepatitis E has been confirmed in Odeke Sub-county in Gulu District. The District Health Educator Mr Okot Lukaki said three cases have been reported. He said a task force has been created to ensure cleanliness especially in the camps. Mr Lukaki said

New hepatitis C virus vaccines study findings reported from Research Center for Infectious Diseases
- (NewsRx.com) -- Fresh data on hepatitis C virus are presented in the report 'Open-label trial of therapeutic immunization with oral V-5 Immunitor (V5) vaccine in patients with chronic hepatitis C.' According to recent research published in the journal

Hepatitis E Risk 'On the Rise'
(UN Integrated Regional Information Networks/All Africa Global Media via COMTEX News Network) -- More people are at risk of contracting the Hepatitis E virus (HEV) in the northern Uganda district of Kitgum, according to a surveillance health report. 'The

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Good News for Non-Responders to HCV Combination Therapy
A Phase 3 trial evaluating ZADAXIN® (thymalfasin) as a potential third component for Hepatitis C traditional combination therapy has just been completed. Although the data is currently being analyzed and won't be available until later in the year, the lead...

Purer, Less Costly Interferon for Hepatitis C and B Treatment
The Taiwan-based biopharmaceutical company PharmaEssentia Corp. is testing P1101, its third-generation PEG-interferon-alpha drug candidate. Because it is a longer-lasting, purer interferon that is less costly to produce, P1101 could enhance the treatment options for Hepatitis C and B....

New Technology May Help Treat Hepatitis
While pharmaceutical companies are racing to find safer, more effective treatments for viral Hepatitis C and B, physicists from Arizona have a unique perspective on accomplishing the same goal. Learn how these scientists believe the virus could be rendered harmelss...

Gastroenterology 1992 Apr;102(4 Pt 1):1306-1308

Absence of hepatitis C viral RNA from saliva and semen of patients with chronic hepatitis C.

Fried MW, Shindo M, Fong TL, Fox PC, Hoofnagle JH, Di Bisceglie AM

Liver Diseases Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

Body fluids from 14 patients with chronic hepatitis C were analyzed for the presence of hepatitis C viral RNA using the polymerase chain reaction. Nucleic acids were extracted from serum, saliva, and semen in guanidinium thiocyanate, subjected to reverse transcription, and then amplified by a double polymerase chain reaction technique using "nested" primers from the highly conserved 5' non-coding region of the hepatitis C virus genome. Hepatitis C viral RNA was found in the serum of all patients in titers ranging between 10(-1) and 10(-3). The hepatitis C viral genome was not detected in any saliva or semen sample. These findings suggest that body fluids of patients with chronic hepatitis C are rarely, if ever, contaminated with the hepatitis C virus. This may help to explain the infrequent transmission of this disease by sexual or close physical contact.

PMID: 1312976, UI: 92201569

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