Hepatitis C, table 2, Histopathology of the Liver in Children With Chronic Hepatitis C Viral Infection

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Histopathology of the Liver in Children With Chronic Hepatitis C Viral Infection

table  2.   Summary of Histopathological Findings
Histological Finding Number of Specimens (%)
Sinusoidal lymphocytosis 37 (74)
  Mild 31 (62)
  Moderate 6 (12)
Steatosis 25 (50)
  Mild 22 (44)
  Moderate 3 (6)
Bile duct damage 14 (28)
  Mild 13 (26)
  Moderate 1 (2)
Lymphoid aggregates and/or follicles 24 (48)
  Aggregates 19 (38)
  Follicles 5 (10)
Venous endothelialitis 20 (40)
  Mild 19 (38)
  Moderate 1 (2)
Increased stainable iron stores 11 (22)
  Reticuloendothelial (RE) only 4 (8)
  RE and hepatocellular 6 (12)
  RE, hepatocellular, and bile ductular 1 (2)
Pigmented macrophages 5 (10)
Portal fibrosis 39 (78)
  Fibrous portal expansion 13 (26)
  Portal-portal or portal-central bridging 11 (22)
  Bridging with architectural distortion 11 (22)
  Cirrhosis 4 (8)
Centrilobular pericellular fibrosis 26 (52)
  Mild 23 (46)
  Moderate 3 (6)

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