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Evaluation of Assays for Antibody to Hepatitis
E Virus by a Serum Panel
| table 1.
Characteristics of 12 Tests to Detect Antibody to HEV
Evaluated by the Serum Panel |
|
| Laboratory |
Test |
Format |
Target HEV Protein |
Expression
|
| ORF(s) |
System |
HEV Strain |
|
| 1 |
1 |
EIA |
Recombinant |
2 |
Insect cells |
Pakistan |
| 2 |
2 |
EIA |
Recombinant |
2 |
Insect cells |
Burma |
| 3 |
3 |
Western blot |
Recombinant |
2 |
Insect cells |
Burma |
| 4 |
4 |
Western blot |
Recombinant |
2, 3 |
E. coli |
China |
| 2 |
5 |
EIA |
Recombinant |
2 |
E. coli |
Burma |
| 5 |
6 |
EIA |
Recombinant |
2, 3 |
E. coli |
Burma, Mexico |
| 6 |
7 |
EIA |
Recombinant* |
2, 3 |
E. coli |
Burma, Mexico |
| 7 |
8 |
EIA |
Recombinant |
2, 3 |
E. coli |
Burma, Mexico |
| 8 |
9 |
EIA |
Synthetic peptides |
3 |
 |
Burma |
| 3 |
10 |
EIA |
Synthetic peptides |
2 |
|
Burma |
| 9 |
11 |
EIA |
Synthetic peptides |
3 |
|
Burma, Mexico |
| 10 |
12 |
EIA |
Synthetic peptides |
2, 3 |
|
Burma, Mexico |
|
| * Artificial
mosaic protein consisting of a series of short linear antigenic
epitopes. |
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Copyright © 1998 by the American Association for the Study
of Liver Diseases.
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