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Evaluation of Assays for Antibody to Hepatitis E Virus by a Serum Panel

table  4.   Detection of Anti-HEV by 12 Different Tests in Sera From Chimpanzees Inoculated With HEV Strains From Various Geographic Regions
Inoculum No. Tested (<6 mo/ 6 mo)dagger Test, No. Anti-HEV Reactive (<6 mo/6 mo)
1 2 3 4 5 6 7 8 9 10 11 12
Mexico 2/3 2/3 2/3 2/3 2/3 2/2 0/0 2/0 0/0 0/0 [1]*/0 0/1 1/0
Mexico 1/3 1/3 1/3 1/3 1/3 1/3 1/0 1/3 1/3 0/0 1/0 0/0 1/1
Mexico 1/3 1/3 1/3 1/3 1/3 1/3 1/2 1/3 1/3 0/0 1/[2] 0/0 1/3
Mexico 1/3 1/3 1/3 1/3 1/3 1/3 0/0 1/3 1/3 0/0 1/[1] 0/0 1/3
Uzbekistan 0/2  /0  /2  /2  /1  /2  /0  /2  /0  /0  /[2]  /0  /0
Pakistan 0/2  /2  /2  /2  /2  /2  /1  /2  /2  /0  /2  /0  /0
Pakistan 3/0 3/ 3/ 3/ 2/ 3/ 0/ 3/ 1/ 0/ 2[1]/ 0/ 1/
Total 8/16 8/14 8/16 8/16 7/15 8/15 2/3 8/13 4/11 0/0 5[2]/2[5] 0/1 5/7
* Numbers in brackets indicate indeterminate test results (weak band by Western blot).
dagger Time of serum collection after inoculation.

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