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J Med Virol 1993 Feb;39(2):163-166
Hepatitis E and Hepatitis C virus infections among French
soldiers with non-A, non-B hepatitis.
Coursaget P, Krawczynski K, Buisson Y, Nizou C, Molinie C
Institut de Virologie de Tours, Faculte de Pharmacie, France.
Serologic markers of HCV and HEV were investigated in 74 French soldiers
with non-A, non-B hepatitis and in 18 patients involved in an outbreak
of non-A,non-B hepatitis in Algeria. Moreover, anti-HCV antibodies were
detected in 13 patients with non-A,non-B hepatitis of parenteral origin.
HEV antibodies were investigated in 61-65% of patients involved in the
2 enterically transmitted outbreaks of non-A,non-B hepatitis observed
in Algeria and Chad. The third cluster of non-A,non-B hepatitis observed
in French soldiers serving in French Guyana is more likely to be attributed
to malaria prophylactic treatment with Amodiaquine than to a viral origin.
HCV infection was observed in 93% of acute or chronic cases associated
with blood transfusion or parenteral drug abuse. Among acute cases, none
of the soldiers who contracted the disease in Africa or in French Guyana
was found to be anti-HCV positive compared to 78% of those who contracted
the disease in France. HCV infections resulted in chronic hepatitis in
61% of cases.
PMID: 8387572, UI: 93253410
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