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J Gastroenterol 1998 Jun;33(3):419-423
Two patients with acute Hepatitis B with suspected
sexual transmission of Hepatitis G virus.
Tanaka E, Nakatsuji Y, Kobayashi M, Orii K, Kiyosawa K Second Department
of Internal Medicine, Shinshu University School of Medicine, Matsumoto,
Japan.
Two patients with acute Hepatitis B with suggested sexual transmission
of Hepatitis G virus (HGV) are reported. A total of 18 patients
with community acquired acute Hepatitis B were analyzed in this
study. Two of the 18 patients (patients 1 and 2) were positive for
serum HGV RNA at the initial consultation. Both patients had had
sexual contact with prostitutes several weeks before the onset of
acute hepatitis, and Hepatitis B virus (HBV) was suggested to be
infected through the sexual contacts. These patients showed no other
history of exposure to possible transmission routes for blood-borne
hepatitis viruses. Patient 1 was diagnosed as with acute HGV infection
because the antibody to HGV envelope-2 protein seroconverted to
positive during the course of acute hepatitis. HGV RNA was negative
in a serum sample collected from patient 2 before the onset of acute
hepatitis, also suggesting acute HGV infection. These results indicate
that in patients 1 and 2 HGV was infected along with HBV through
sexual contact. The clinical manifestations of acute hepatitis in
the two patients with HGV co-infection did not differ from those
in the 16 patients with HBV infection alone.
PMID: 9658324, UI: 98322460
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