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Determinants of Outcome of Compensated Hepatitis C Virus-Related Cirrhosis

table  3.   Univariate and Multivariate Analyses of Prognostic Factors for Decompensation Unrelated to HCC
Variable Number of Patients Univariate Analysis
Multivariate Analysis
P* Relative RiskDagger (95% CI) Pdagger Relative RiskDagger (95% CI)
Age at diagnosis       63 y 72
>63 y 31 .01 3.0 (1.2-7.4) NS  ---
ALT  76 IU/L 43
>76 IU/L 60 .04 2.6 (1-6.5) NS  ---
Albumin 3.4 g/dL 89
<3.4 g/dL 14 .005 3.6 (1.4-9.6) NS  ---
Prothrombin time 63% 86
<63% 17 .003 3.7 (1.4-9) NS  ---
Platelets 102 × 109/L 79
<102 × 109/L 24 .05 2.3 (1-5.9) NS ---
Child-Pugh score A 94
B 9 .0004 5.4 (1.9-15.5) NS  ---
IFN Yes 59
  No 44 .001 4.5 (1.7-13.4) .03 3.0 (1.1-8.7)
Abbreviations: NS, not significant; CI, confidence interval.
* P values were obtained by using the log-rank test.
dagger P values were obtained by using Cox regression analysis.
Relative risks were calculated by comparing classes with Cox regression analysis.

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