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Determinants of Outcome of Compensated Hepatitis C Virus-Related Cirrhosis
table  4.   Univariate and Multivariate Analyses of Prognostic Factors for Survival

Variable§ Number of Patients Univariate Analysis
Multivariate Analysis
P* Relative RiskDagger (95% CI) Pdagger Relative RiskDagger  (95% CI)

Splenomegaly No 78
Yes 25 .04 2.4 (1-6.2) NS
Alk. Ph. 87 IU/L 83
>87 IU/L 20 .03 2.6 (1-6.4) NS  
Albumin 3.4 g/dL 89
<3.4 g/dL 14 <.0001 6.0 (2.4-15.2) <.0001 7.8 (2.9-20.1)
Prothrombin time 63% 86
<63% 17 <.0001 5.7 (2.3-14.4) NS  
Bilirubin 1.11 mg/dL 77
>1.11 mg/dL 26 .02 2.7 (1.1-6.8) NS  
Platelets 102 × 109/L 79
<102 × 109/L 24 .03 2.7 (1.1-6.8) NS
Child-Pugh score A 94
B 9 <.0001 8.6 (2.5-30.3) NS  
IFN Yes 59
  No 44 <.0001 6.0 (2.2-16.3) .0002 7.6 (2.6-22)

Abbreviations: NS, not significant; CI, confidence interval; Alk. Ph., alkaline phosphatase.
* P values were obtained by using the log-rank test.
dagger P values were obtained by using Cox regression analysis.
Dagger Relative risks were calculated by comparing classes with Cox regression analysis.
§ For multivariate analysis, variables are shown in the order of entry into the model.

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