Acute Hepatitis C from Unsafe Injections
Disease The CDC has concluded an investigation of a clinic in Nevada that reported an outbreak of Hepatitis C Virus (HCV) in 6 people that resulted from unsafe injection procedures. Here's what happened:Hepatitis C is a reportable infection to the
CDC: Syringe reuse linked to hepatitis C outbreak
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Free blood test for widespread hepatitis B
A quarter century after the first hepatitis B vaccine became commercially available, rates of acute infection with the liver-scarring virus have plummeted in the United States, but the disease remains endemic in Asia - and 1 in 10 of the estimated 10.3
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What You Must Know About Alcoholic Hepatitis
This much-needed synopsis of alcoholic hepatitis reminds us that you don't need to be a heavy drinker to suffer from this condition. Looking over the causes, risk factors and complications of alcoholic hepatitis will motivate anyone with liver concerns to...
15 Tips for Managing Interferon-Ribavirin Side Effects
Finding new ways to manage the side effects of Hepatitis C combination therapy adds to a person’s likelihood of conquering the virus....
New Mexico Offers Free Hepatitis C Hotline
Finally being recognized as the widespread, public health problem that it is, the New Mexico Department of Health has taken a giant step forward to help people with Hepatitis C. By launching a new, toll-free phone number, locals concerned about...
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Fibrosis & Cirrhosis
Cirrhosis
Pathology
A key ingredient is fibrosis, whose development and extent
depends upon the interplay of many factors. The progression of fibrosis
to cirrhosis similarly depends upon the extent of injury, the presence
of continuing damage, and the liver's reaction to these agents.
Thus the lesion of cirrhosis is not static, and the features seen
depend upon the activity and stage of the disease involved. Classification
of pathology in cirrhosis may indicate the prominent features found
in any one specimen but does not provide etiologic information nor
a complete morphologic description of the pathology.
The common classification of the histopathology in cirrhosis: Micronodular
cirrhosis is characterized by thin, regular bands of connective
tissue and by small nodules (up to 1 cm in diameter) that vary little
in size. Typically, terminal hepatic venules or portal tracts are
difficult to identify. Macronodular cirrhosis is characterized by
nodules that vary in size (up to 5 cm in diameter), are often multinodular,
and contain portal tracts and terminal hepatic venules. Broad fibrous
bands of varying thickness surround the nodules. Collapse of the
normal liver architecture is suggested by the concentration of portal
tracts within the fibrous scars. Mixed cirrhosis (incomplete septal
cirrhosis) combines elements of micro- and macronodular cirrhosis.
Regeneration within the nodules is less conspicuous, and hepatic
venules and portal tracts are seen more often.
Source:The Merck Manual
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