Viral Hepatitis C support group to begin meeting
AUBURN, CALIF Placer County Health and Human Services will begin hosting a hepatitis C support group for anyone who wants to know more about the disease and its treatment. The confidential group is offered at no cost, is open to the public and will meet
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Since medical spas are offering more treatments involving the use of needles, the potential for Hepatitis C transmission is rising. Learn about some of the spa treatment techniques that pose hepatitis transmission dangers, as well as five ways to increase...
Hepatitis B Treatment May Reduce Pancreatic Cancer Risk
While several theories are attempting to explain the connection, scientists are unsure why those with Hepatitis B appear to have a 2 1/2 fold increase in risk for developing pancreatic cancer. Once the link is understood, Hepatitis B treatment may...
Damage Scores for Liver Biopsy
Less Than
More Than
HISTOLOGY ACTIVITY INDEX (HAI - Knodell Score)
Periportal ± Bridging Necrosis
Score
Intralobular Degeneration and Focal Necrosis
Score
Portal Inflammation
Score
Fibrosis
Score
None
0
None
0
No portal inflammation
0
No fibrosis
0
Mild piecemeal necrosis
1
Mild (acidophilic bodies, ballooning degeneration
and/or scattered foci of hepatocellular necrosis in 1/3 of lobules or
nodules)
1
Mild (sprinkling of inflammatory cells in 1/3 of portal tracts)
1
Fibrous portal expansion
1
Moderate piecemeal necrosis (involves50% of the circumference of most portal tracts)
3
Moderate (involvement of 1/3-2/3 of lobules
or nodules)
3
Moderate (increased inflammatory cells in
1/3-2/3 of portal tracts)
3
Bridging Fibrosis (portal-portal or portal-central
linkage)
3
Marked piecemeal necrosis (involves
50% of the circumference of most portal tracts)
4
Marked (involvement of2/3 of lobules
or nodules)
4
Marked (dense packing of inflammatory cells
in2/3 of portal tracts)
4
Cirrhosis
4
Moderate piecemeal necrosis plus
bridging necrosis
5
ReferenceKnodell RG, et al.
Marked piecemeal necrosis plus bridging
necrosis
6
Multilobular necrosis
10
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