Hepatitis Central

The latest research & treatment news about Hepatitis C infection, diagnosis, symptoms and treatments.

High Incidence of Allograft Cirrhosis in Hepatitis C Virus Genotype 1b Infection Following Transplantation: Relationship With Rejection Episodes

table  2.   Evolution of Activity and Fibrosis in the First 5 Years After Liver Transplantation
Score First Year Second Year Third Year Fourth Year Fifth Year
Grade (activity)* n = 78 n = 56 n = 35 n = 19 n = 13
  No hepatitis, n (%) 5 (6.4) 1 (1.8) 3 (8.6) 1 (5.3) 0 (0)
  Minimal, n (%) 20 (25.6) 9 (16.1) 5 (14.3) 2 (10.5) 2 (15.4)
  Mild, n (%) 17 (21.8) 12 (21.4) 7 (20) 4 (21.1) 5 (53.8)
  Moderate, n (%) 31 (39.7) 25 (44.6) 13 (37.1) 8 (42.1) 4 (30.8)
  Severe, n (%) 5 (6.4) 9 (16.1) 7 (20) 4 (21.1) 2 (15.4)
Stage (fibrosis) n = 78 n = 57 n =  35  n = 18 n = 13
  None, n (%) 44 (56.4) 24 (42.1) 15 (42.9) 5 (27.8) 4 (30.8)
  Fibrous portal expansion, n (%) 27 (34.6) 21 (36.8) 10 (28.6) 9 (50) 6 (46.2)
  Bridging fibrosis, n (%) 4 (5.1) 9 (15.8) 7 (20) 1 (5.6) 3 (23.1)
  Cirrhosis, n (%) 3 (3.8) 3 (5.3) 3 (8.6) 3 (16.7) 0 (0)
* Activity was determined by combining the HAI (Knodell) scores for periportal necrosis (0-6), lobular degeneration and necrosis (0-4), and portal inflammation (0-4), and defined as follows: 1-2, minimal; 3-6, mild; 7-10, moderate; 11-14, severe.

Return To Article

table Of Contents

Site Topics

  • Frequently Asked Questions

    Some of our most commonly asked questions and our answers to them.

  • HCV Symptoms

    You'll find links to a comprehensive symptoms list, as well as various studies and discussions about Hepatitis C symptoms.

  • Lab Tests

    What they are and what they mean. Helps you interpret & understand all the various hepatitis lab tests likely to be encountered.

  • Hepatitis C Genotypes

    Learn about Hepatitis C Genotypes and their variants.

  • Viral Load

    Provides detailed information on how to analyze and interpret viral load numbers as well as a link to a convenient Viral Load Chart.

  • What is...?

    Learn more about various Hepatitis C related topics, including HCV, Ascites, Biopsies, and much more.

  • HCV Medicines

    Numerous links to studies, info sheets, FAQs, and analysis of Ribavirin/Rebetron medicines.

  • Glossary

    Commonly used medical terms and definitions.

  • Hepatitis C Doctors

    A state-by-state and worldwide reference listing physicians who treat HCV, including an email link to submit your physician for inclusion.

  • Biopsy Info

    A comprehensive resource of information relating to the liver biopsy.

  • Cirrhosis

    Many discussions and analyses of cirrhosis, including causes, complications, pathology, symptoms, and much more.

  • Liver Cancer

    Liver Cancer/Hepatocellular Carcinoma studies, info sheets, FAQs, and analysis.

  • Liver Disease Medicines

    An exhaustive list of links to studies, info sheets, FAQs, and analysis of the various drugs used to treat liver disease.

  • Hep-Central Email List

    Sign up to learn about advances and breakthroughs in Hepatitis C research, including information about medical and complementary treatments.

  • HCV Links

    Convenient links to other sites external to Hepatitis-Central.

  • HCV Transmission

    Information about the transmission of Hepatitis C.

  • HCV Natural Remedies

    A number of herbal products useful in the management of liver disease.

  • HCV Books

    Recommended reading for those interested in hepatitis information.

  • Hepatitis C Forum

    A Bulletin Board for discussions on hepatitis, treatments, etc.

  • Hepatitis C Activism

    An easy way to get involved in urging our government to do more for Hepatitis C awareness and treatment research.

Advertisement(s)

Advertisement