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High Incidence of Allograft Cirrhosis in Hepatitis C Virus Genotype 1b Infection Following Transplantation: Relationship With Rejection Episodes

table  4.   Histological and Biochemical Data at 1 Year Predictive of HCV-Related Graft Cirrhosis
Patients With
Cirrhosis
(n = 9) 		Patients
Without
Cirrhosis
(n = 48) 		P
Activity 7.6 ± 3.4 4.4 ± 3.1 .008
Periportal necrosis 2.7 ± 1.7 1.3 ± 1.4 .02
Intralobular degeneration 2.2 ± 1.2 1.3 ± 1.1 .02
Portal inflammation 2.7 ± 1.3 1.8 ± 1.3 .09
Fibrosis 0.7 ± 0.5 0.4 ± 0.6 .18
AST (U/L) 114 ± 40 64 ± 44 .002
ALT (U/L) 176 ± 85 95 ± 80 .008
Abbreviation: AST, aspartate transaminase; ALT, alanine transaminase.

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