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CDC: Syringe reuse linked to hepatitis C outbreak
A hepatitis C outbreak was caused by workers improperly reusing syringes and medicine vials at a Las Vegas clinic, federal health officials said Friday.The Centers for Disease Control and Prevention was contacted by state health officials earlier this


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What You Must Know About Alcoholic Hepatitis
This much-needed synopsis of alcoholic hepatitis reminds us that you don't need to be a heavy drinker to suffer from this condition. Looking over the causes, risk factors and complications of alcoholic hepatitis will motivate anyone with liver concerns to...

15 Tips for Managing Interferon-Ribavirin Side Effects
Finding new ways to manage the side effects of Hepatitis C combination therapy adds to a person’s likelihood of conquering the virus....

New Mexico Offers Free Hepatitis C Hotline
Finally being recognized as the widespread, public health problem that it is, the New Mexico Department of Health has taken a giant step forward to help people with Hepatitis C. By launching a new, toll-free phone number, locals concerned about...

Portal Hypertension, What is it?

Increased portal vein pressure caused by intrinsic liver disease or obstruction in the extrahepatic portal vein or hepatic venous outflow tract.

The portal venous system carries all blood from the abdominal GI tract, spleen, pancreas, and gallbladder back to the heart through the liver. The portal vein is formed by the union of the superior mesenteric and splenic veins. At the porta hepatis it divides into the right and left branches, which are segmentally distributed intrahepatically; the terminal portal venules drain into the sinusoids. In the resting state, the portal vein carries about 1 to 1.2 L/min of blood (about 75% of total hepatic blood flow) and provides 2/3 of the liver's O2 supply. The portal vein is valveless; thus, pressure in the portal system depends on the product of input from blood flow in the portal vein and total hepatic resistance to outflow. Normal pressure in the portal vein is between 1 and 4 mm Hg higher than the free pressure in the hepatic vein, or up to 6 mm Hg higher than right atrial pressure. Portal hypertension is defined as pressures above these limits.



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Source: The Merck Manual

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Updated 17 May 2008