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Altered Mice Offer Ideal Liver Disease Drug Testing Model

March 1, 2010

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Solving the ongoing challenge of how to test potential liver disease drugs before experimenting on humans, Salk Institute researchers have perfected a system where medications can be tested in mice with mostly human livers.

Mouse With Human Liver: New Model for Treatment of Liver Disease

ScienceDaily (Feb. 23, 2010) -- How do you study-and try to cure in the laboratory-an infection that only humans can get? A team led by Salk Institute researchers does it by generating a mouse with an almost completely human liver. This "humanized" mouse is susceptible to human liver infections and responds to human drug treatments, providing a new way to test novel therapies for debilitating human liver diseases and other diseases with liver involvement such as malaria.

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http://www.sciencedaily.com/releases/2010/02/100222182144.htm

Posted by Editors at March 1, 2010 10:46 AM

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